Hyperthyroidism means excessive thyroid hormone production, from hyper meaning above normal, thyroid referring to the thyroid gland, and ism meaning condition. It causes increased metabolism, weight loss, rapid heartbeat, anxiety, tremor, and heat intolerance. Graves disease is the most common cause. Hypothyroidism means insufficient thyroid hormone production, from hypo meaning below normal. It causes decreased metabolism, weight gain, fatigue, cold intolerance, and constipation. Hashimoto thyroiditis is the most common cause.