The Apgar score is assessed at one and five minutes after birth, evaluating five criteria each scored 0, 1, or 2: appearance or skin color, pulse or heart rate, grimace or reflex irritability, activity or muscle tone, and respiration. A total score of 7 to 10 is normal and reassuring, 4 to 6 indicates moderate distress requiring intervention, and 0 to 3 indicates severe distress requiring aggressive resuscitation. Heart rate is the most important indicator of neonatal well-being. A rate below 100 requires positive pressure ventilation.