What is the reversal agent for benzodiazepine overdose?

Flumazenil is the specific reversal agent for benzodiazepine overdose. It works by competitively binding to the GABA-A receptor at the benzodiazepine binding site, displacing the benzodiazepine and reversing its sedative and respiratory depressant effects. Flumazenil is administered intravenously with effects beginning within one to two minutes. However, its duration of action is shorter than most benzodiazepines, so resedation can occur and repeat doses may be needed. ---