Clopidogrel vs. Aspirin: Key Differences

Clopidogrel, brand name Plavix, is an antiplatelet medication that inhibits the P2Y12 adenosine diphosphate receptor on platelets, preventing platelet activation and aggregation through a different pathway than aspirin. It is used for acute coronary syndrome, after coronary stent placement, and for stroke prevention. Dual antiplatelet therapy combining aspirin and clopidogrel is standard after stent placement for up to twelve months.