What is the difference between typical and atypical antipsychotics?

Typical, or first-generation, antipsychotics like haloperidol and chlorpromazine primarily block dopamine D2 receptors and are effective for positive symptoms of schizophrenia such as hallucinations and delusions but frequently cause extrapyramidal symptoms. Atypical, or second-generation, antipsychotics like risperidone, olanzapine, quetiapine, and clozapine block both dopamine and serotonin receptors, treating both positive and negative symptoms with fewer movement side effects.